Neuropeptides Peptides
Signaling peptides active in the nervous system that modulate neurotransmission, pain perception, and neuroendocrine function. Includes substance P analogs, neuropeptide Y, and related compounds.
Other Categories
Related Categories
Dihexa
Dihexa (PNB-0408): angiotensin IV-derived peptide that potentiates HGF/c-Met signaling. Covers preclinical cognitive enhancement research, oral bioavailability, and safety considerations.
Kisspeptin
Kisspeptin: Master HPG axis regulator for fertility research. Covers GnRH neuron activation, Phase 2 trial data, IVF applications, and safety.
Nemifitide
Nemifitide (INN-00835): pentapeptide MIF-1 analog with rapid-onset antidepressant effects (5-7 days). Phase 3 clinical trials for major depressive disorder.
Neuropeptide Y
Neuropeptide Y (NPY): 36-amino acid endogenous peptide regulating stress resilience, appetite, and anxiety. Intranasal delivery studied for depression and PTSD.
Oveporexton
Oveporexton (TAK-861): first-in-class oral OX2R-selective agonist for narcolepsy type 1. Phase 3 FirstLight/RadiantLight trial results, mechanism, dosing, and NDA filing status.
PE-22-28
PE-22-28: synthetic spadin analog TREK-1 potassium channel blocker. Preclinical antidepressant effects and hippocampal neurogenesis within 4 days of treatment.
Rapastinel
Rapastinel (GLYX-13): NMDA receptor glycine-site partial agonist. Covers phase 2 antidepressant results, failed phase 3 trials, and rapid-acting mechanism.
VIP
VIP: Vasoactive Intestinal Peptide guide. Covers vasodilation, gut motility, CIRS/mold illness research, circadian effects, and immune modulation.
Head-to-Head Comparisons
Detailed comparisons between neuropeptides peptides covering mechanisms, efficacy, side effects, and research evidence.
Related Articles
Dihexa (PNB-0408): Structure, Solubility, Paper Controversy & Research Status in 2026
Deep-dive into Dihexa (PNB-0408): chemical structure (C27H44N4O5, MW 504.66), solubility data, the retracted Benoist 2014 paper, HGF/c-Met controversy, and where research stands in 2026.
guidePeptide Therapy for Brain Health: Neuroprotection, Cognition, and Recovery
Comprehensive guide to peptides for brain health covering neurotrophic factors, neuroprotective agents, anxiolytics, and experimental cognitive enhancers. Includes cerebrolysin, semax, selank, BPC-157, dihexa, pinealon, SS-31, and rapastinel.
guideNootropic Peptide Stacks: What Research Says About Combining Cognitive Peptides
Evidence-based review of nootropic peptide stacking, including Semax+Selank combinations, BDNF upregulation stacks, and neuroprotective synergies.
research-reviewPeptides for Brain Injury and Neuroprotection: TBI, Stroke, and Neurodegeneration Research
Research review of neuroprotective peptides for TBI, stroke, and neurodegeneration, including Semax, Davunetide, BPC-157, and Dihexa.
guideBest Nootropic Peptides for Cognitive Enhancement: 2026 Guide
Comprehensive 2026 guide to 8 nootropic peptides for cognitive enhancement — dihexa, semax, selank, cerebrolysin, PE-22-28, davunetide, pinealon, and humanin — grouped by mechanism including BDNF upregulation, synaptogenesis, neuroprotection, and anxiolytic pathways.
guideBest Peptides for Menopause Symptoms: 2026 Research Guide
Research guide covering peptides studied for menopause symptoms including hot flashes, bone loss, cognitive changes, skin aging, sleep disruption, and hormonal regulation.
Research Tools
Use our interactive tools to explore neuropeptides peptides further.