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🧬Peptide Protocol Wiki

Anti-aging Peptides

Explore our collection of anti-aging peptides with comprehensive research-backed information.

Anti-Aging & LongevityWeight Loss & Metabolism

5-Amino-1MQ

5-Amino-1MQ is a selective NNMT inhibitor that boosts NAD+ levels. Preclinical data shows anti-obesity and muscle function benefits. No human trials published.

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Anti-Aging & LongevityWeight Loss & Metabolism

Carnosine

Carnosine: endogenous dipeptide with anti-glycation, antioxidant, and pH-buffering properties. Phase 2 trials in diabetes, cognition, and anti-aging applications.

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Growth HormoneAnti-Aging & Longevity

CJC-1295 DAC

CJC-1295 DAC: Long-acting GHRH analog with extended half-life. Covers Drug Affinity Complex mechanism, GH/IGF-1 elevation, dosing, and side effects.

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Growth HormoneAnti-Aging & Longevity

CJC-1295 without DAC

CJC-1295 No DAC (Mod GRF 1-29): Short-acting GHRH analog. Covers pulsatile GH release, Ipamorelin stack synergy, dosing, and side effects.

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Muscle & Bone HealthAnti-Aging & Longevity

Enobosarm

Enobosarm (Ostarine/GTx-024): oral SARM for muscle preservation during GLP-1 weight loss. QUALITY Phase 2b positive. PLATEAU trial with tirzepatide planned.

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Anti-Aging & LongevityImmune Support

Epitalon

Epitalon (Epithalone) is not FDA or EMA approved. Review telomerase activation data, Khavinson research, pineal gland effects, and Thymalin comparisons.

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Anti-Aging & LongevityImmune Support

FOXO4-DRI

FOXO4-DRI: Senolytic peptide targeting senescent cells. Covers FOXO4-p53 disruption, aging reversal research by Baar et al., dosing, and limitations.

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Healing & Tissue RepairAnti-Aging & LongevitySkin & Hair

GHK-Cu

GHK-Cu: Copper tripeptide for skin healing and anti-aging. Covers collagen stimulation, wound repair, hair growth, and topical vs injectable use.

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Immune SupportAnti-Aging & Longevity

Glutathione

Glutathione: The body's master antioxidant tripeptide. Covers redox cycling, detoxification, immune support, IV vs oral bioavailability, and dosing.

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Anti-Aging & LongevityBrain & Neuroprotection

Humanin

Humanin: 24-amino acid mitochondrial-derived peptide with anti-apoptotic and neuroprotective effects. Research in Alzheimer's, aging, and metabolic disease.

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Growth HormoneAnti-Aging & Longevity

Ipamorelin

Ipamorelin: Selective GH secretagogue without cortisol/prolactin spikes. Covers GHSR mechanism, clinical research, dosing protocols, and side effects.

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Anti-Aging & LongevityBrain & Neuroprotection

Klotho Peptides

Comprehensive klotho peptide research guide covering KP1 and KP6 klotho-derived peptides for kidney fibrosis and diabetic kidney disease, alpha-klotho protein for cognitive enhancement and neuroprotection, FGF23 signaling, anti-aging mechanisms, and the latest clinical trial developments in 2026.

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Anti-Aging & LongevityCognitive EnhancementMitochondrial & Cellular Energy

NAD+

NAD+ (Nicotinamide Adenine Dinucleotide): Essential coenzyme for cellular energy, DNA repair, and anti-aging research. Covers sirtuins, PARPs, CD38, NAD+ decline with aging, precursor strategies, and clinical evidence.

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Anti-Aging & LongevitySkin & Hair

OS-01 (Peptide 14)

OS-01 (Peptide 14) is a senotherapeutic decapeptide targeting cellular senescence via PP2A modulation. Published RCT data shows skin barrier and aging improvements.

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Cognitive EnhancementAnti-Aging & Longevity

Pinealon

Pinealon (EDR): Bioregulatory neuroprotective tripeptide. Covers epigenetic gene regulation, cognitive enhancement research, and Khavinson science.

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Anti-Aging & LongevityImmune Support

PNC-27

PNC-27: p53-derived anticancer peptide guide. Covers selective HDM-2 binding on cancer membranes, pore-forming cytotoxicity, and research limitations.

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Growth HormoneAnti-Aging & Longevity

Sermorelin

Sermorelin: GHRH(1-29) analog for growth hormone stimulation. Covers pulsatile GH release, anti-aging research, dosing, and GH secretagogue comparison.

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Skin & HairAnti-Aging & Longevity

SNAP-8

SNAP-8: Botox-like cosmeceutical peptide for wrinkle reduction. Covers SNARE complex inhibition, topical formulation research, and Argireline comparison.

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Mitochondrial & Cellular EnergyAnti-Aging & LongevityVascular & Cardiovascular

SS-31

SS-31 (Elamipretide): Cardiolipin-targeting mitochondrial peptide. Covers Barth syndrome Phase 3 data, heart failure research, dosing, and trial results.

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Anti-Aging & LongevityImmune Support

Tat-Beclin-1

Tat-Beclin-1: cell-permeable autophagy-inducing peptide from beclin 1/HIV Tat. Preclinical antiviral, anticancer, and neuroprotective research applications.

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Immune SupportAnti-Aging & Longevity

Thymalin

Thymalin: Thymic peptide bioregulator for immune restoration. Covers T-cell support, pineal-thymic axis aging research, Khavinson studies, and dosing.

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Anti-Aging & LongevityImmune Support

Vilon

Vilon (Lys-Glu): synthetic dipeptide bioregulator with immunomodulatory and geroprotective effects. Preclinical research in lifespan extension and chromatin reactivation.

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Head-to-Head Comparisons

Detailed comparisons between anti-aging peptides covering mechanisms, efficacy, side effects, and research evidence.

Related Articles

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The Hallmarks of Aging: Which Peptides Target Which?

Definitive mapping of the 12 hallmarks of aging to specific peptide interventions including Epitalon, FOXO4-DRI, SS-31, MOTS-c, and NAD+.

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13 Best Anti-Aging Peptides (2026): Ranked by Clinical Evidence

From senolytic FOXO4-DRI to mitochondrial SS-31, we ranked 13 anti-aging peptides by clinical trial evidence across 6 mechanisms. See which have human data vs. animal-only studies.

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Peptides for Energy and Mitochondrial Health: What the Research Shows

Research guide to 7 peptides targeting energy and mitochondrial health — SS-31 (elamipretide), MOTS-c, humanin, carnosine, thymosin alpha-1, tesamorelin, and sermorelin — with clinical evidence, mechanisms, and practical context.

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Peptides for Physical Performance and Endurance: What the Research Shows

An evidence-based guide to peptides studied for physical performance, endurance, and exercise capacity — including MOTS-c, carnosine, tesamorelin, AOD-9604, cortistatin, and BPC-157.

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Best Growth Hormone Peptides Ranked: 2026 Evidence-Based Guide

A ranked comparison of 8 growth hormone secretagogues and related peptides — from FDA-approved tesamorelin to IGF-1 LR3 — evaluating each on mechanism of action, clinical evidence strength, key advantages, and known drawbacks.

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Peptide Stacking Safety: Synergies, Interactions, and Protocol Design

A safety-focused guide to combining peptides — covering known synergistic combinations, contraindicated pairings, timing and administration principles, recommended bloodwork monitoring, and red flags to watch for during stacked protocols.

Research Tools

Use our interactive tools to explore anti-aging peptides further.